| 06.03 | Strade Bianche 1. Chantal van den Broek-Blaak (SD Worx) 2. Elisa Longo Borghini (Trek-Segafredo) 3. Anna van den Breggen (SD Worx) |
| 21.03 | Trofeo Alfredo Binda 1. Elisa Longo Borghini (Trek-Segafredo) 2. Marianne Vos (Jumbo-Visma) 3. Cecilie Uttrup Ludwig (FDJ) |
| 25.03 | Oxclean Classic Brugge-De Panne 1. Grace Brown (BikeExchange) 2. Emma Norsgaard (Movistar) 3. Jolien d’Hoore (SD Worx) |
| 28.03 | Gent-Wevelgem 1. Marianne Vos (Jumbo-Visma) 2. Lotte Kopecky (Liv) 3. Lisa Brennauer (Ceratizit-WNT) |
| 04.04 | Ronde van Vlaanderen 1. Annemiek van Vleuten (Movistar) 2. Lisa Brennauer (Ceratizit-WNT) 3. Grace Brown (BikeExchange) |
| 18.04 | Amstel Gold Race 1. Marianne Vos (Jumbo-Visma) 2. Demi Vollering (SD Worx) 3. Annemiek van Vleuten (Movistar) |
| 21.04 | La Fleche Wallonne 1. Anna van der Breggen (SD Worx) 2. Kassia Niewiadoma (Canyon Sram) 3. Elisa Longo Borghini (Trek-Segafredo) |
| 25.04 | Liege-Bastogne-Liege 1. Demi Vollering (SD Worx) 2. Annemiek van Vleuten (Movistar) 3. Elisa Longo Borghini (Trek-Segafredo) |
| 20.08 – 23.05 | Vuelta a Burgos 1. Anna van der Breggen (SD Worx) 2. Annemiek van Vleuten (Movistar) 3. Demi Vollering (SD Worx) |
| 18.07 | La Course by Le Tour 1. Demi Vollering (SD Worx) 2. Cecilie Uttrup Ludwig (FDJ) 3. Marianne Vos (Jumbo-Visma) |
| 31.07 | Classica San Sebastian |
| 12.08 – 15.08 | Ladies Tour of Norway |
| 24.08 – 29.08 | Simac Ladies Tour |
| 30.08 | GP de Plouay |
| 03.09 – 05.09 | Ceratizit Challenge by la Vuelta |
| 02.10 | Paris-Roubaix |
| 04.10 – 09.10 | The Women’s Tour |
| 14.10 – 16.10 | Tour of Chongming Island |
| 19.10 | Tour of Guangxi |
| 23.10 | Ronde van Drenthe |
